Ontology highlight
ABSTRACT:
SUBMITTER: Bohler S
PROVIDER: S-EPMC6853143 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Clinical and translational science 20190715 6
Four complementary approaches were used to investigate acetaminophen overdose as a risk factor for Parkinson's disease (PD). Circulating microRNAs (miRNAs) serum profiles from acetaminophen-overdosed patients were compared with patients with terminal PD, revealing four shared miRNAs. Similarities were found among molecular structures of dopamine (DA), acetaminophen, and two known PD inducers indicating affinity for dopaminergic transport. Potential interactions between acetaminophen and the huma ...[more]