Ontology highlight
ABSTRACT:
SUBMITTER: Yu K
PROVIDER: S-EPMC6854986 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Yu Kun K Wang Rong-Xiang RX Li Meng-Hui MH Sun Tie-Cheng TC Zhou Yi-Wen YW Li Yuan-Yuan YY Sun Li-Hua LH Zhang Bao-Lu BL Lian Zheng-Xing ZX Xue Song-Guo SG Liu Yi-Xun YX Deng Shou-Long SL
Oxidative medicine and cellular longevity 20191020
<h4>Background/aims</h4>Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by abnormal hormone levels in peripheral blood and poor-quality oocytes. PCOS is a pathophysiological syndrome caused by chronic inflammation and oxidative stress. The aim of this study was to investigate the mechanism of melatonin regulation on androgen production and antioxidative damage in granulosa cells from PCOS patients with hypoestrogenia and hyperandrogenia.<h4>Methods</h4>Cumulus-oocyte comp ...[more]