Ontology highlight
ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC6855210 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Wang Tao T Wang Xiao-Tong XT Lai Ran R Ling Hong-Wei HW Zhang Fan F Lu Qian Q Lv Dong-Mei DM Yin Xiao-Xing XX
Frontiers in pharmacology 20191107
The objective of this study was to investigate whether <i>MTNR1B</i> gene variants influence repaglinide response in Chinese patients with newly diagnosed type 2 diabetes mellitus (T2DM). A total of 300 patients with T2DM and 200 control subjects were enrolled to identify <i>MTNR1B</i> rs10830963 and rs1387153 genotypes by real-time polymerase chain reaction (PCR), with subsequent high-resolution melting (HRM) analysis. Ninety-five patients with newly diagnosed T2DM were randomly selected to und ...[more]