Ontology highlight
ABSTRACT:
SUBMITTER: Han F
PROVIDER: S-EPMC6856370 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Han Fei F Konkalmatt Prasad P Mokashi Chaitanya C Kumar Megha M Zhang Yanrong Y Ko Allen A Farino Zachary J ZJ Asico Laureano D LD Xu Gaosi G Gildea John J Zheng Xiaoxu X Felder Robin A RA Lee Robin E C REC Jose Pedro A PA Freyberg Zachary Z Armando Ines I
Scientific reports 20191114 1
The Wnt/β-catenin pathway is one of the most conserved signaling pathways across species with essential roles in development, cell proliferation, and disease. Wnt signaling occurs at the protein level and via β-catenin-mediated transcription of target genes. However, little is known about the underlying mechanisms regulating the expression of the key Wnt ligand Wnt3a or the modulation of its activity. Here, we provide evidence that there is significant cross-talk between the dopamine D<sub>2</su ...[more]