Propolis induces Ca2+ signaling in immune cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Adachi T
PROVIDER: S-EPMC6856514 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Propolis induces Ca<sup>2+</sup> signaling in immune cells.
Adachi Takahiro T Yoshikawa Soichiro S Tezuka Hiroyuki H Tsuji Noriko M NM Ohteki Toshiaki T Karasuyama Hajime H Kumazawa Toshihiko T
Bioscience of microbiota, food and health 20190824 4
Propolis possesses several immunological functions. We recently generated a conditional Ca<sup>2+</sup> biosensor yellow cameleon (YC3.60) transgenic mouse line and established a five-dimensional (5D) (x, y, z, time, and Ca<sup>2+</sup> signaling) system for intravital imaging of lymphoid tissues, including Peyer's patches (PPs). To assess the effects of propolis on immune cells, we analyzed Ca<sup>2+</sup> signaling <i>in vitro</i> and <i>in vivo</i> using CD11c-Cre/YC3.60<sup>flox</sup> transg ...[more]
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