Ontology highlight
ABSTRACT:
SUBMITTER: Kim JT
PROVIDER: S-EPMC6856584 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Kim Jong-Tae JT Cho Hee Jun HJ Park Sang Yoon SY Oh Byung Moo BM Hwang Yo Sep YS Baek Kyoung Eun KE Lee Young-Ha YH Kim Hee Cheol HC Lee Hee Gu HG
Journal of Cancer 20191015 24
DNA replication and sister chromatid cohesion 1 (DSCC1) combines with chromosome transmission-fidelity protein 18 (CTF18) to form a CTF18-DSCC1-CTF8 (CTF18-1-8) module, which in combination with CTF18-replication factor C (RFC) acts as a proliferating cell nuclear antigen (PCNA) loader during DNA replication-associated processes. It was found that DSCC1 was overexpressed in tumor tissues from patients with colon cancer and that the survival probability of patients with colon cancer was lower whe ...[more]