Influential factors of postoperative pain trajectories in patients receiving intravenous patient-controlled analgesia: a single-centre cohort study in Taiwan.
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ABSTRACT: OBJECTIVES:We aimed to investigate the factors associated with variations in postoperative pain trajectories over time in patients using intravenous patient-controlled analgesia (IV-PCA) for postoperative pain. DESIGN:Retrospective cohort study. SETTING:A single medical centre in Taiwan. PARTICIPANTS:Patients receiving IV-PCA after surgery. PRIMARY AND SECONDARY OUTCOME MEASURES:Primary outcome was the postoperative pain scores. RESULTS:A total of 3376 patients and 20?838 pain score observations were analysed using latent curve models. Female and longer anaesthesia time increased the baseline level of pain (p=0.004?and 0.003, respectively), but abdominal surgery and body weight decreased it (both p<0.001). Regarding the trend of pain resolution, lower abdominal surgery steepened the slope (p<0.001); older age, American Society of Anesthesiologists (ASA) class ?3?and longer anaesthesia time tended to flatten the slope (p<0.001, =0.019?and <0.001, respectively). PCA settings did not affect the variations in postoperative pain trajectories. CONCLUSIONS:Patient demographics, ASA class, anaesthesia time and surgical sites worked together to affect postoperative pain trajectories in patients receiving IV-PCA. Latent curve models provided valuable information about the dynamic and complex relationships between the pain trajectories and their influential factors.
SUBMITTER: Tai YH
PROVIDER: S-EPMC6858203 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
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