Ontology highlight
ABSTRACT:
SUBMITTER: DeRosha DE
PROVIDER: S-EPMC6858550 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
DeRosha Daniel E DE Chilkuri Vijay G VG Van Stappen Casey C Bill Eckhard E Mercado Brandon Q BQ DeBeer Serena S Neese Frank F Holland Patrick L PL
Nature chemistry 20191014 11
Iron-sulfur clusters are emerging as reactive sites for the reduction of small-molecule substrates. However, the four-coordinate iron sites of typical iron-sulfur clusters rarely react with substrates, implicating three-coordinate iron. This idea is untested because fully sulfide-coordinated three-coordinate iron is unprecedented. Here we report a new type of [4Fe-3S] cluster that features an iron centre with three bonds to sulfides, and characterize examples of the cluster in three oxidation le ...[more]