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Patient-specific reconstruction of volumetric computed tomography images from a single projection view via deep learning.


ABSTRACT: Tomographic imaging using penetrating waves generates cross-sectional views of the internal anatomy of a living subject. For artefact-free volumetric imaging, projection views from a large number of angular positions are required. Here we show that a deep-learning model trained to map projection radiographs of a patient to the corresponding 3D anatomy can subsequently generate volumetric tomographic X-ray images of the patient from a single projection view. We demonstrate the feasibility of the approach with upper-abdomen, lung, and head-and-neck computed tomography scans from three patients. Volumetric reconstruction via deep learning could be useful in image-guided interventional procedures such as radiation therapy and needle biopsy, and might help simplify the hardware of tomographic imaging systems.

SUBMITTER: Shen L 

PROVIDER: S-EPMC6858583 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Patient-specific reconstruction of volumetric computed tomography images from a single projection view via deep learning.

Shen Liyue L   Zhao Wei W   Xing Lei L  

Nature biomedical engineering 20191028 11


Tomographic imaging using penetrating waves generates cross-sectional views of the internal anatomy of a living subject. For artefact-free volumetric imaging, projection views from a large number of angular positions are required. Here we show that a deep-learning model trained to map projection radiographs of a patient to the corresponding 3D anatomy can subsequently generate volumetric tomographic X-ray images of the patient from a single projection view. We demonstrate the feasibility of the  ...[more]

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