Ontology highlight
ABSTRACT:
SUBMITTER: Cingam S
PROVIDER: S-EPMC6861552 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Cingam Shashank S Flatow-Trujillo Lainey L Andritsos Leslie A LA Arana Yi Cecilia C
Journal of blood medicine 20191114
Polycythemia vera (PV) is a rare myeloproliferative neoplasm (MPN) associated with significant impairment in quality of life (QoL) due to disease-related symptoms and complications. Assessment of disease burden constitutes standard monitoring of symptoms and response. Conventional treatments for MPN, such as hydroxyurea, phlebotomy, or interferon, have not shown a significant impact in QoL or patient-reported outcomes (PRO). Ruxolitinib (RUX) is a JAK2 inhibitor approved for patients intolerant ...[more]