Ontology highlight
ABSTRACT:
SUBMITTER: Cristina V
PROVIDER: S-EPMC6862353 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Cristina Valerie V Herrera-Gómez Ruth Gabriela RG Szturz Petr P Espeli Vittoria V Siano Marco M
International journal of molecular sciences 20191030 21
Head and neck squamous cell carcinoma (HNSCC) is often diagnosed at an advanced stage and has a dismal prognosis. Nearly 10 years after the approval of cetuximab, anti-PD1/PD-L1 checkpoint inhibitors are the first drugs that have shown any survival benefit for the treatment on platinum-refractory recurrent/metastatic (R/M) HNSCC. Furthermore, checkpoint inhibitors are better tolerated than chemotherapy. The state of the art in the treatment of R/M HNSCC is changing, thanks to improved results fo ...[more]