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Antimicrobial-resistant Gram-negative colonization in infants from a neonatal intensive care unit in Thailand.

ABSTRACT: Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum ?-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay.

SUBMITTER: Roberts T

PROVIDER: S-EPMC6863035 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Antimicrobial-resistant Gram-negative colonization in infants from a neonatal intensive care unit in Thailand.

Roberts T T Limmathurotsakul D D Turner P P Day N P J NPJ Vandepitte W P WP Cooper B S BS

The Journal of hospital infection 20190414 2

Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-re ...[more]

PMID: 30995491

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