Ontology highlight
ABSTRACT:
SUBMITTER: Baron CS
PROVIDER: S-EPMC6863042 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Baron Chloé S CS Barve Aditya A Muraro Mauro J MJ van der Linden Reinier R Dharmadhikari Gitanjali G Lyubimova Anna A de Koning Eelco J P EJP van Oudenaarden Alexander A
Cell 20191001 2
Much of current molecular and cell biology research relies on the ability to purify cell types by fluorescence-activated cell sorting (FACS). FACS typically relies on the ability to label cell types of interest with antibodies or fluorescent transgenic constructs. However, antibody availability is often limited, and genetic manipulation is labor intensive or impossible in the case of primary human tissue. To date, no systematic method exists to enrich for cell types without a priori knowledge of ...[more]