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Prediction and associations of preterm birth and its subtypes with eicosanoid enzymatic pathways and inflammatory markers.


ABSTRACT: Endogenous signaling molecules derived from lipids, peptides, and DNA, are important regulators of physiological processes during pregnancy. The effect of their collective impact on preterm birth (delivery?

SUBMITTER: Aung MT 

PROVIDER: S-EPMC6863859 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Prediction and associations of preterm birth and its subtypes with eicosanoid enzymatic pathways and inflammatory markers.

Aung Max T MT   Yu Youfei Y   Ferguson Kelly K KK   Cantonwine David E DE   Zeng Lixia L   McElrath Thomas F TF   Pennathur Subramaniam S   Mukherjee Bhramar B   Meeker John D JD  

Scientific reports 20191119 1


Endogenous signaling molecules derived from lipids, peptides, and DNA, are important regulators of physiological processes during pregnancy. The effect of their collective impact on preterm birth (delivery < 37 weeks gestation) is understudied. We aimed to characterize the associations and predictive capacity of an extensive panel of eicosanoids, immune biomarkers, oxidative stress markers, and growth factors towards preterm birth and its subtypes. We conducted a cross-sectional study of pregnan  ...[more]

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