Genetic evidence for assortative mating on alcohol consumption in the UK Biobank.
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ABSTRACT:
SUBMITTER: Howe LJ
PROVIDER: S-EPMC6864067 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Genetic evidence for assortative mating on alcohol consumption in the UK Biobank.
Howe Laurence J LJ Lawson Daniel J DJ Davies Neil M NM St Pourcain Beate B Lewis Sarah J SJ Davey Smith George G Hemani Gibran G
Nature communications 20191119 1
Alcohol use is correlated within spouse-pairs, but it is difficult to disentangle effects of alcohol consumption on mate-selection from social factors or the shared spousal environment. We hypothesised that genetic variants related to alcohol consumption may, via their effect on alcohol behaviour, influence mate selection. Here, we find strong evidence that an individual's self-reported alcohol consumption and their genotype at rs1229984, a missense variant in ADH1B, are associated with their pa ...[more]
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