Ontology highlight
ABSTRACT:
SUBMITTER: Harmsen RAG
PROVIDER: S-EPMC6864559 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Harmsen Rianne A G RAG Tuveng Tina R TR Antonsen Simen G SG Eijsink Vincent G H VGH Sørlie Morten M
Molecules (Basel, Switzerland) 20191026 21
Chitin, an insoluble linear polymer of β-1,4-<i>N</i>-acetyl-d-glucosamine (GlcNAc; A), can be converted to chitosan, a soluble heteropolymer of GlcNAc and d-glucosamine (GlcN; D) residues, by partial deacetylation. In nature, deacetylation of chitin is catalyzed by enzymes called chitin deacetylases (CDA) and it has been proposed that CDAs could be used to produce chitosan. In this work, we show that CDAs can remove up to approximately 10% of <i>N</i>-acetyl groups from two different (α and β) ...[more]