Ontology highlight
ABSTRACT:
SUBMITTER: Lian T
PROVIDER: S-EPMC6865161 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Lian Ting T Gaur Uma U Wu Q I QI Tu Jianbo J Sun Boyuan B Yang Deying D Fan Xiaolan X Mao Xueping X Yang Mingyao M
Genetics research 20180201
Dietary restriction (DR) is widely regarded as a viable intervention to extend lifespan and healthspan in diverse organisms. The precise molecular regulatory mechanisms are largely unknown. Epigenetic modifications are not stable upon DR and also keep changing with age. Here, we employed whole genome bisulfite sequencing to determine the DNA methylation changes upon DR in adult Drosophila. Our results indicate that although a low level of DNA methylation exists in the adult Drosophila genome, th ...[more]