Molecular genetics of thyroid cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Reba? M
PROVIDER: S-EPMC6865173 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
The pathogenesis of the development and progression of thyroid cancer (TC) is far from being clear at present. Accumulated evidence suggests that it is a complex polygenic disorder for which genetic factors play an important role in disease aetiology. Here we review the literature to report the genetic variations and alterations that have been described in the aetiology of TC. The functional effects of some mutations and single nucleotide polymorphisms on TC are validated, establishing the role ...[more]
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