Prevalence of positive islet autoantibody in type 2 diabetes patients: a cross-sectional study in a Chinese community.

ABSTRACT:

Background

Islet autoantibodies occur in type 2 diabetes. Our study aimed to investigate the prevalence of positive islet autoimmunity in community patients with type 2 diabetes.

Methods

A total of 495 community patients with type 2 diabetes were recruited using the method of cluster sampling in this cross-sectional study. Three islet autoantibodies including glutamic acid decarboxylase antibody (GADA), insulin autoantibody (IAA) and islet cell antibody (ICA) were measured, and clinical characteristics involved in those individuals were evaluated.

Results

The positive rate of islet autoantibodies was 28.5% in total, while combinations of different autoantibodies were rarely seen. Compared with GADA-negative group, positive counterparts significantly tended to have low

SUBMITTER: Gao X 

PROVIDER: S-EPMC6865362 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature