Aberrant visual pathway development in albinism: From retina to cortex.
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ABSTRACT:
SUBMITTER: Ather S
PROVIDER: S-EPMC6865554 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
Aberrant visual pathway development in albinism: From retina to cortex.
Ather Sarim S Proudlock Frank Anthony FA Welton Thomas T Morgan Paul S PS Sheth Viral V Gottlob Irene I Dineen Rob A RA
Human brain mapping 20181204 3
Albinism refers to a group of genetic abnormalities in melanogenesis that are associated neuronal misrouting through the optic chiasm. We perform quantitative assessment of visual pathway structure and function in 23 persons with albinism (PWA) and 20 matched controls using optical coherence tomography (OCT), volumetric magnetic resonance imaging (MRI), diffusion tensor imaging and visual evoked potentials (VEP). PWA had a higher streamline decussation index (percentage of total tractography str ...[more]
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