Dataset Information

Neural processing of social interaction: Coordinate-based meta-analytic evidence from human neuroimaging studies.

ABSTRACT: While the action observation and mentalizing networks are considered to play complementary roles in understanding others' goals and intentions, they might be concurrently engaged when processing social interactions. We assessed this hypothesis via three activation-likelihood-estimation meta-analyses of neuroimaging studies on the neural processing of: (a) social interactions, (b) individual actions by the action observation network, and (c) mental states by the mentalizing network. Conjunction analyses and direct comparisons unveiled overlapping and specific regions among the resulting maps. We report quantitative meta-analytic evidence for a "social interaction network" including key nodes of the action observation and mentalizing networks. An action-social interaction-mentalizing gradient of activity along the posterior temporal cortex highlighted a hierarchical processing of interactions, from visuomotor analyses decoding individual and shared intentions to in-depth inferences on actors' intentional states. The medial prefrontal cortex, possibly in conjunction with the amygdala, might provide additional information concerning the affective valence of the interaction. This evidence suggests that the functional architecture underlying the neural processing of interactions involves the joint involvement of the action observation and mentalizing networks. These data might inform the design of rehabilitative treatments for social cognition disorders in pathological conditions, and the assessment of their outcome in randomized controlled trials.

SUBMITTER: Arioli M

PROVIDER: S-EPMC6865826 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Neural processing of social interaction: Coordinate-based meta-analytic evidence from human neuroimaging studies.

Arioli Maria M Canessa Nicola N

Human brain mapping 20190511 13

While the action observation and mentalizing networks are considered to play complementary roles in understanding others' goals and intentions, they might be concurrently engaged when processing social interactions. We assessed this hypothesis via three activation-likelihood-estimation meta-analyses of neuroimaging studies on the neural processing of: (a) social interactions, (b) individual actions by the action observation network, and (c) mental states by the mentalizing network. Conjunction a ...[more]

PMID: 31077492

Similar Datasets

Project description:INTRODUCTION:About 30-40% of the population report sexual dysfunction. Although it is well known that the brain controls sexual behavior, little is known about the neural basis of sexual dysfunction. AIM:To assess convergence of altered brain activity associated with sexual dysfunction across available functional imaging studies. METHODS:We used activation likelihood estimation meta-analysis to quantify interstudy concordance across 14 functional imaging studies reporting 179 foci from 40 individual analyses involving 191 subjects with sexual dysfunction and 123 controls. MAIN OUTCOME MEASURE:Activation likelihood estimation scores were used to assess convergence of findings. RESULTS:Consistently decreased brain activity associated with sexual dysfunction was identified in the dorsal anterior cingulate cortex, ventral striatum, dorsal midbrain, anterior midcingulate cortex, and lateral orbitofrontal cortex. CLINICAL IMPLICATION:These findings can serve as a basis for further studies on the pathophysiology of this highly common disorder with the view to development of more-specific treatment strategies. STRENGTH & LIMITATIONS:Findings are based on an observer-independent meta-analysis that provides robust evidence for and anatomic localization of altered brain activity related to sexual dysfunction. Our analysis cannot distinguish between the putative sources of sexual dysfunction, but it provides a more ubiquitous and general pattern of related altered neural activity. CONCLUSION:The identified regions have previously been shown to be critically involved in mediating sexual arousal and to be part of the sympathetic division of the autonomic nervous system. This suggests that the disturbance of brain activity associated with sexual dysfunction primarily affects sexual arousal already at early stages that are controlled by the sympathetic nervous system. Poeppl TB, Langguth B, Laird AR, et al. Meta-analytic Evidence for Neural Dysactivity Underlying Sexual Dysfunction. J Sex Med 2019;16:614-617.

Dataset Information

Neural processing of social interaction: Coordinate-based meta-analytic evidence from human neuroimaging studies.

Publications

Neural processing of social interaction: Coordinate-based meta-analytic evidence from human neuroimaging studies.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets