Ontology highlight
ABSTRACT:
SUBMITTER: Chang YS
PROVIDER: S-EPMC6867519 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Chang Yi Shin YS Owen Julia P JP Pojman Nicholas J NJ Thieu Tony T Bukshpun Polina P Wakahiro Mari L J ML Marco Elysa J EJ Berman Jeffrey I JI Spiro John E JE Chung Wendy K WK Buckner Randy L RL Roberts Timothy P L TP Nagarajan Srikantan S SS Sherr Elliott H EH Mukherjee Pratik P
Human brain mapping 20160524 8
Copy number variants at the 16p11.2 chromosomal locus are associated with several neuropsychiatric disorders, including autism, schizophrenia, bipolar disorder, attention-deficit hyperactivity disorder, and speech and language disorders. A gene dosage dependence has been suggested, with 16p11.2 deletion carriers demonstrating higher body mass index and head circumference, and 16p11.2 duplication carriers demonstrating lower body mass index and head circumference. Here, we use diffusion tensor im ...[more]