Ontology highlight
ABSTRACT:
SUBMITTER: Dimitriu T
PROVIDER: S-EPMC6868128 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Dimitriu Tatiana T Medaney Frances F Amanatidou Elli E Forsyth Jessica J Ellis Richard J RJ Raymond Ben B
Scientific reports 20191120 1
Plasmids may maintain antibiotic resistance genes in bacterial populations through conjugation, in the absence of direct selection pressure. However, the costs and benefits of conjugation for plasmid and bacterial fitness are not well understood. Using invasion and competition experiments with plasmid mutants we explicitly tested how conjugation contributes to the maintenance of a plasmid bearing a single extended-spectrum ß-lactamase (ESBL) gene (bla<sub>CTX-M-14</sub>). Surprisingly, conjugati ...[more]