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Interventions for idiopathic steroid-resistant nephrotic syndrome in children.


ABSTRACT:

SUBMITTER: Liu ID 

PROVIDER: S-EPMC6868353 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Interventions for idiopathic steroid-resistant nephrotic syndrome in children.

Liu Isaac D ID   Willis Narelle S NS   Craig Jonathan C JC   Hodson Elisabeth M EM  

The Cochrane database of systematic reviews 20191121 11


<h4>Background</h4>The majority of children who present with their first episode of nephrotic syndrome achieve remission with corticosteroid therapy. Children who fail to respond to corticosteroids in the first episode of nephrotic syndrome (initial resistance) or develop resistance after one or more responses to corticosteroids (delayed resistance) may be treated with immunosuppressive agents including calcineurin inhibitors (CNI) (cyclosporin or tacrolimus) and with non-immunosuppressive agent  ...[more]

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2021-02-16 | GSE145969 | GEO