Ontology highlight
ABSTRACT:
SUBMITTER: Dans PD
PROVIDER: S-EPMC6868377 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Dans Pablo D PD Balaceanu Alexandra A Pasi Marco M Patelli Alessandro S AS Petkevičiūtė Daiva D Walther Jürgen J Hospital Adam A Bayarri Genís G Lavery Richard R Maddocks John H JH Orozco Modesto M
Nucleic acids research 20191201 21
We present a multi-laboratory effort to describe the structural and dynamical properties of duplex B-DNA under physiological conditions. By processing a large amount of atomistic molecular dynamics simulations, we determine the sequence-dependent structural properties of DNA as expressed in the equilibrium distribution of its stochastic dynamics. Our analysis includes a study of first and second moments of the equilibrium distribution, which can be accurately captured by a harmonic model, but wi ...[more]