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ABSTRACT: Background
The main aims of this study were to describe trends and outcomes during admission for infective endocarditis (IE) in people ??40 years old with or without type 2 diabetes distributed in five time-periods (2001-2003; 2004-2006; 2007-2009; 2010-2012 and 2013-2015), using Spanish national hospital discharge data.Methods
We estimated admission rates by diabetes status. We analyzed comorbidity, therapeutic procedures, and outcomes. We built Poisson regression models to compare the adjusted time-trends in admission rates. Type 2 diabetes cases were matched with controls using propensity score matching (PSM). We tested in-hospital mortality (IHM) in logistic regression analyses.Results
We identified 16,626 hospitalizations in patients aged ??40 years for IE in Spain, 2001-2015. The incidence of IE increased significantly from 6.0/100,000 per year to 13.1/100,000 per year (p?ConclusionIncidence rates of IE in Spain, among those with and without T2DM, have increased during the period 2001-2015 with significantly higher incidence rates in the T2DM population. In our population based study and after PSM we found that T2DM was not a predictor of IHM in IE.
SUBMITTER: de Miguel-Yanes JM
PROVIDER: S-EPMC6868776 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
de Miguel-Yanes José M JM Jiménez-García Rodrigo R Hernández-Barrera Valentín V de Miguel-Díez Javier J Méndez-Bailón Manuel M Muñoz-Rivas Nuria N Pérez-Farinós Napoleón N López-de-Andrés Ana A
Cardiovascular diabetology 20191121 1
<h4>Background</h4>The main aims of this study were to describe trends and outcomes during admission for infective endocarditis (IE) in people ≥ 40 years old with or without type 2 diabetes distributed in five time-periods (2001-2003; 2004-2006; 2007-2009; 2010-2012 and 2013-2015), using Spanish national hospital discharge data.<h4>Methods</h4>We estimated admission rates by diabetes status. We analyzed comorbidity, therapeutic procedures, and outcomes. We built Poisson regression models to comp ...[more]