Ontology highlight
ABSTRACT:
SUBMITTER: Majewska J
PROVIDER: S-EPMC6871536 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Majewska Joanna J Kaźmierczak Zuzanna Z Lahutta Karolina K Lecion Dorota D Szymczak Aleksander A Miernikiewicz Paulina P Drapała Jarosław J Harhala Marek M Marek-Bukowiec Karolina K Jędruchniewicz Natalia N Owczarek Barbara B Górski Andrzej A Dąbrowska Krystyna K
Frontiers in immunology 20191114
In therapeutic phage applications oral administration is a common and well-accepted delivery route. Phages applied <i>per os</i> may elicit a specific humoral response, which may in turn affect phage activity. We present specific anti-phage antibody induction in mice receiving therapeutic staphylococcal bacteriophage A3R or 676Z in drinking water. The schedule comprised: (1) primary exposure to phages for 100 days, followed by (2) diet without phage for 120 days, and (3) secondary exposure to th ...[more]