Ontology highlight
ABSTRACT:
SUBMITTER: Chantaren P
PROVIDER: S-EPMC6873726 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Chantaren Patchima P Jongkhajornpong Passara P Ueta Mayumi M Puangsricharern Vilavun V Lekhanont Kaevalin K Pisuchpen Phattrawan P Prabhasawat Pinnita P Suphapeetiporn Kanya K Kinoshita Shigeru S
Clinical and translational allergy 20191122
<h4>Purpose</h4>Our meta-analysis of several ethnic groups (Japanese, Korean, Indian, Brazilian) revealed a significant genome-wide association between cold medicine-related SJS/TEN (CM-SJS/TEN) with severe ocular complications (SOC) and <i>IKZF1</i> SNPs, suggesting that <i>IKZF1</i> might be a potential marker for susceptibility to CM-SJS/TEN with SOC. In this study, we examined the association between CM-SJS/TEN with SOC and the <i>IKZF1</i> SNPs in the Thai population.<h4>Methods</h4>57 CM-S ...[more]