Ontology highlight
ABSTRACT:
SUBMITTER: Lonetti A
PROVIDER: S-EPMC6873958 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lonetti Annalisa A Pession Andrea A Masetti Riccardo R
Frontiers in pediatrics 20191115
Acute myeloid leukemia (AML) is a hematopoietic disorder characterized by numerous cytogenetic and molecular aberrations that accounts for ~25% of childhood leukemia diagnoses. The outcome of children with AML has increased remarkably over the past 30 years, with current survival rates up to 70%, mainly due to intensification of standard chemotherapy and improvements in risk classification, supportive care, and minimal residual disease monitoring. However, childhood AML prognosis remains unfavor ...[more]