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Multiple drug combinations of bortezomib, lenalidomide, and thalidomide for first-line treatment in adults with transplant-ineligible multiple myeloma: a network meta-analysis.

ABSTRACT:

SUBMITTER: Piechotta V

PROVIDER: S-EPMC6876545 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Multiple drug combinations of bortezomib, lenalidomide, and thalidomide for first-line treatment in adults with transplant-ineligible multiple myeloma: a network meta-analysis.

Piechotta Vanessa V Jakob Tina T Langer Peter P Monsef Ina I Scheid Christof C Estcourt Lise J LJ Ocheni Sunday S Theurich Sebastian S Kuhr Kathrin K Scheckel Benjamin B Adams Anne A Skoetz Nicole N

The Cochrane database of systematic reviews 20191125 11

<h4>Background</h4>Multiple myeloma is a bone marrow-based hematological malignancy accounting for approximately two per cent of cancers. First-line treatment for transplant-ineligible individuals consists of multiple drug combinations of bortezomib (V), lenalidomide (R), or thalidomide (T). However, access to these medicines is restricted in many countries worldwide.<h4>Objectives</h4>To assess and compare the effectiveness and safety of multiple drug combinations of V, R, and T for adults with ...[more]

PMID: 31765002

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