Nationwide Outcome of Gastrectomy with En-Bloc Partial Pancreatectomy for Gastric Cancer.

ABSTRACT: BACKGROUND:Radical gastrectomy is the cornerstone of the treatment of gastric cancer. For tumors invading the pancreas, en-bloc partial pancreatectomy may be needed for a radical resection. The aim of this study was to evaluate the outcome of gastrectomies with partial pancreatectomy for gastric cancer. METHODS:Patients who underwent gastrectomy with or without partial pancreatectomy for gastric or gastro-oesophageal junction cancer between 2011 and 2015 were selected from the Dutch Upper GI Cancer Audit (DUCA). Outcomes were resection margin (pR0) and Clavien-Dindo grade ??III postoperative complications and survival. The association between partial pancreatectomy and postoperative complications was analyzed with multivariable logistic regression. Overall survival of patients with partial pancreatectomy was estimated using the Kaplan-Meier method. RESULTS:Of 1966 patients that underwent gastrectomy, 55 patients (2.8%) underwent en-bloc partial pancreatectomy. A pR0 resection was achieved in 45 of 55 patients (82% versus 85% in the group without additional resection, P?=?0.82). Clavien-Dindo grade ??III complications occurred in 21 of 55 patients (38% versus 17%, P?

SUBMITTER: van der Werf LR 

PROVIDER: S-EPMC6877485 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature