Ontology highlight
ABSTRACT:
SUBMITTER: Wu TN
PROVIDER: S-EPMC6877517 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Wu Tai-Na TN Lee Chau-Shoun CS Wu Bo-Jian BJ Sun Hsiao-Ju HJ Chang Chieh-Hsing CH Chen Chun-Ying CY Chen Chih-Ken CK Wu Lawrence Shih-Hsin LS Cheng Andrew Tai-Ann AT
Scientific reports 20191125 1
Immune dysfunction is implicated in the etiology of bipolar disorder. The single-nucleotide polymorphism rs17026688 in the gene encoding glutamate decarboxylase-like protein 1 (GADL1) has been found to be associated with lithium response in Han Chinese patients with bipolar I disorder (BDI). However, whether patients with GADL1 polymorphisms have different immunophenotypes is unknown. To address this issue, differences in the immune profiles based on analysis of peripheral blood mononuclear cell ...[more]