Ontology highlight
ABSTRACT:
SUBMITTER: Heo K
PROVIDER: S-EPMC6877527 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Heo Kyoo K Park Young-Ha YH Lee Kyung-Ah KA Kim Joonwon J Ham Hyeong-In HI Kim Byung-Gee BG Lee Won-Jae WJ Seok Yeong-Jae YJ
Nature communications 20191125 1
Biofilm formation protects bacteria from stresses including antibiotics and host immune responses. Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae, but the underlying mechanisms remain unclear. Here, we show that EIIA<sup>Glc</sup>, a component of the phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS), regulates the intracellular concentration of the cyclic dinucleotide c-di-GMP, and thus biofilm formation. The availability of preferred ...[more]