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Unsolved severe chronic rhinosinusitis elucidated by extensive CFTR genotyping.


ABSTRACT: Severe chronic rhinosinusitis in children should alert clinicians and extensive CFTR genotyping should be performed. We propose that thorough clinical and functional assessment in severe chronic rhinosinusitis is valuable to discover rare mutations which could be treated by CFTR correctors to postpone pulmonary infection.

SUBMITTER: Degrugillier F 

PROVIDER: S-EPMC6878083 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Severe chronic rhinosinusitis in children should alert clinicians and extensive <i>CFTR</i> genotyping should be performed. We propose that thorough clinical and functional assessment in severe chronic rhinosinusitis is valuable to discover rare mutations which could be treated by CFTR correctors to postpone pulmonary infection. ...[more]

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