Ontology highlight
ABSTRACT:
SUBMITTER: de Nijs B
PROVIDER: S-EPMC6878213 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
ACS sensors 20191101 11
Quantitative applications of surface-enhanced Raman spectroscopy (SERS) often rely on surface partition layers grafted to SERS substrates to collect and trap-solvated analytes that would not otherwise adsorb onto metals. Such binding layers drastically broaden the scope of analytes that can be probed. However, excess binding sites introduced by this partition layer also trap analytes outside the plasmonic "hotspots". We show that by eliminating these binding sites, limits of detection (LODs) can ...[more]