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Determining the Safety and Efficacy of Enhanced Recovery Protocols in Major Oncologic Surgery: An Institutional NSQIP Analysis.


ABSTRACT: BACKGROUND:Enhanced-recovery (ER) protocols are increasingly being utilized in surgical practice. Outside of colorectal surgery, however, their feasibility, safety, and efficacy in major oncologic surgery have not been proven. This study compared patient outcomes before and after multispecialty implementation of ER protocols at a large, comprehensive cancer center. METHODS:Surgical cases performed from 2011 to 2016 and captured by an institutional NSQIP database were reviewed. Following exclusion of outpatient and emergent surgeries, 2747 cases were included in the analyses. Cases were stratified by presence or absence of ER compliance, defined by preoperative patient education and electronic medical record order set-driven opioid-sparing analgesia, goal-directed fluid therapy, and early postoperative diet advancement and ambulation. RESULTS:Approximately half of patients were treated on ER protocols (46%) and the remaining on traditional postoperative (TP) protocols (54%). Treatment on an ER protocol was associated with decreased overall complication rates (20% vs. 33%, p?

SUBMITTER: Marcus RK 

PROVIDER: S-EPMC6878764 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Determining the Safety and Efficacy of Enhanced Recovery Protocols in Major Oncologic Surgery: An Institutional NSQIP Analysis.

Marcus Rebecca K RK   Lillemoe Heather A HA   Rice David C DC   Mena Gabriel G   Bednarski Brian K BK   Speer Barbra B BB   Ramirez Pedro T PT   Lasala Javier D JD   Navai Neema N   Williams Wendell H WH   Kim Bradford J BJ   Voss Rachel K RK   Gottumukkala Vijaya N VN   Aloia Thomas A TA  

Annals of surgical oncology 20190109 3


<h4>Background</h4>Enhanced-recovery (ER) protocols are increasingly being utilized in surgical practice. Outside of colorectal surgery, however, their feasibility, safety, and efficacy in major oncologic surgery have not been proven. This study compared patient outcomes before and after multispecialty implementation of ER protocols at a large, comprehensive cancer center.<h4>Methods</h4>Surgical cases performed from 2011 to 2016 and captured by an institutional NSQIP database were reviewed. Fol  ...[more]

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