Ontology highlight
ABSTRACT:
SUBMITTER: Schnappauf O
PROVIDER: S-EPMC6878845 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Schnappauf Oskar O Aksentijevich Ivona I
Rheumatology (Oxford, England) 20191101 Suppl 6
Systemic autoinflammatory diseases (SAIDs) are a group of inflammatory disorders caused by dysregulation in the innate immune system that leads to enhanced immune responses. The clinical diagnosis of SAIDs can be difficult since individually these are rare diseases with considerable phenotypic overlap. Most SAIDs have a strong genetic background, but environmental and epigenetic influences can modulate the clinical phenotype. Molecular diagnosis has become essential for confirmation of clinical ...[more]