Ontology highlight
ABSTRACT:
SUBMITTER: Peng L
PROVIDER: S-EPMC6878914 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Peng Liu L Guo Jin-Cheng JC Long Lin L Pan Feng F Zhao Jian-Mei JM Xu Li-Yan LY Li En-Min EM
BioMed research international 20191030
Flavoproteins and their interacting proteins play important roles in mitochondrial electron transport, fatty acid degradation, and redox regulation. However, their clinical significance and function in esophageal squamous cell carcinoma (ESCC) are little known. Here, using survival analysis and machine learning, we mined 179 patient expression profiles with ESCC in GSE53625 from the Gene Expression Omnibus (GEO) database and constructed a signature consisting of two flavoprotein genes (GPD2 and ...[more]