Ontology highlight
ABSTRACT:
SUBMITTER: Parmar A
PROVIDER: S-EPMC6878938 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Parmar A A Chan K K W KKW Ko Y J YJ
Current oncology (Toronto, Ont.) 20191101 Suppl 1
Therapeutic options for chemorefractory metastatic colorectal cancer (mcrc) have significantly expanded since 2009. The oral targeted therapies regorafenib and trifluridine/tipiracil have been established to be efficacious and safe in patients with mcrc who have progressed beyond 2 or more lines of chemotherapy. Evidence for the use of immunotherapy in a subgroup of this patient population is also encouraging, particularly in patients with mcrc that exhibits high microsatellite instability or de ...[more]