Ontology highlight
ABSTRACT:
SUBMITTER: Luo X
PROVIDER: S-EPMC6879555 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Luo Xiao X Chi Weilai W Deng Minghua M
Frontiers in genetics 20191120
Convolutional neural network (CNN) based methods have outperformed conventional machine learning methods in predicting the binding preference of DNA-protein binding. Although studies in the past have shown that more convolutional kernels help to achieve better performance, visualization of the model can be obscured by the use of many kernels, resulting in overfitting and reduced interpretation because the number of motifs in true models is limited. Therefore, we aim to arrive at high performance ...[more]