Ontology highlight
ABSTRACT:
SUBMITTER: Leininger SE
PROVIDER: S-EPMC6879781 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Leininger Sarah E SE Narayan Karthik K Deutsch Carol C O'Brien Edward P EP
Biochemistry 20190611 47
As the influence of translation rates on protein folding and function has come to light, the mechanisms by which translation speed is modulated have become an important issue. One mechanism entails the generation of force by the nascent protein. Cotranslational processes, such as nascent protein folding, the emergence of unfolded nascent chain segments from the ribosome's exit tunnel, and insertion of the nascent chain into or translocation of the nascent chain through membranes, can generate fo ...[more]