Ontology highlight
ABSTRACT:
SUBMITTER: Tapia-Castillo A
PROVIDER: S-EPMC6880399 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Tapia-Castillo Alejandra A Guanzon Dominic D Palma Carlos C Lai Andrew A Barros Eric E Allende Fidel F Vecchiola Andrea A Fardella Carlos E CE Salomón Carlos C Carvajal Cristian A CA
Journal of translational medicine 20191127 1
<h4>Background</h4>The "nonclassic" apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by low plasma renin activity (PRA), high serum cortisol (F) to cortisone (E) ratio, low cortisone, high Fractional Excretion of potassium (FEK) and normal-elevated systolic blood pressure (SBP). An early detection and/or identification of novel biomarkers of this phenotype could avoid the progression or future complications ...[more]