Dataset Information

Genome-Wide identification of doublesex and Mab-3-Related transcription factor (DMRT) genes in nile tilapia (oreochromis niloticus).

ABSTRACT: Doublesex and Mab-3-related transcription factor (DMRT) gene family is extensively known for its contribution in sex determination and differentiation across phyla. Here we report the identification of five DM (doublesex and mab-3) domain genes in the Nile tilapia which includes DMRT1, DMRTa2, DMRT2a, DMRT2b and DMRT3a. The full-length sequence of DMRT genes ranges from 3526 (DMRTA2) to 1471bp (DMRT1) which encode putative proteins series from 469 to 372 amino acids. All the DMRT proteins contained at least one conserved DNA-binding DM domain. Sub-cellular localization and gene ontology revealed DMRT1 protein is maximum localized in nuclear region and gene ontology analysis showed the molecular function of 48.2%, biological process 43.6% and cellular component 25%. Chromosomal location and synteny analysis displayed that DMRT genes mostly cluster linkage group 12. Altogether, our findings provide vital genomic information for future studies of biochemical, physiological, and phylogenetic studies on DMRT genes in teleost.

SUBMITTER: Zafar I

PROVIDER: S-EPMC6881697 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Genome-Wide identification of doublesex and Mab-3-Related transcription factor (DMRT) genes in nile tilapia (<i>oreochromis niloticus)</i>.

Zafar Imran I Rather Mohd Ashraf MA Dhandare Bhushan C BC

Biotechnology reports (Amsterdam, Netherlands) 20191111

Doublesex and Mab-3-related transcription factor (DMRT) gene family is extensively known for its contribution in sex determination and differentiation across phyla. Here we report the identification of five DM (doublesex and mab-3) domain genes in the Nile tilapia which includes DMRT1, DMRTa2, DMRT2a, DMRT2b and DMRT3a. The full-length sequence of DMRT genes ranges from 3526 (DMRTA2) to 1471bp (DMRT1) which encode putative proteins series from 469 to 372 amino acids. All the DMRT proteins contai ...[more]

PMID: 31799146

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Dataset Information

Genome-Wide identification of doublesex and Mab-3-Related transcription factor (DMRT) genes in nile tilapia (oreochromis niloticus).

Publications

Genome-Wide identification of doublesex and Mab-3-Related transcription factor (DMRT) genes in nile tilapia (<i>oreochromis niloticus)</i>.

Similar Datasets

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