Ontology highlight
ABSTRACT:
SUBMITTER: Gou ZP
PROVIDER: S-EPMC6882005 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Gou Zhong-Ping ZP Zhang Wei W Liang Xiu-Fang XF Wang Ying Y Mou Ju-Hong JH Li Mei M Zhang Ya Y Feng Ping P
BMC complementary and alternative medicine 20191127 1
<h4>Background</h4>This study aims to assess the tolerability and safety of DQTM tablet, which contains a complex mixture of Salvia miltiorrhiza salvianolic acids and Panax notoginseng saponins.<h4>Methods</h4>A double-blind, randomized, placebo-controlled phase I dose escalation study was conducted in 84 healthy volunteers. In a single ascending dose study, active ingredients were administered in various doses (90, 270, 540, 1080, 1800, 2880, 4320 or 5760 mg) to 60 subjects in cohorts 1-8. In a ...[more]