Ontology highlight
ABSTRACT:
SUBMITTER: Purcell RV
PROVIDER: S-EPMC6882162 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Purcell Rachel V RV Schmeier Sebastian S Lau Yee Chen YC Pearson John F JF Frizelle Francis A FA
BMC cancer 20191127 1
<h4>Background</h4>Post-surgical staging is the mainstay of prognostic stratification for colorectal cancer (CRC). Here, we compare TNM staging to consensus molecular subtyping (CMS) and assess the value of subtyping in addition to stratification by TNM.<h4>Methods</h4>Three hundred and eight treatment-naïve colorectal tumours were accessed from our institutional tissue bank. CMS typing was carried out using tumour gene-expression data. Post-surgical TNM-staging and CMS were analysed with respec ...[more]