MiR-9-5p Inhibits Glioblastoma Cells Proliferation Through Directly Targeting FOXP2 (Forkhead Box P2).
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ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC6882274 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
MiR-9-5p Inhibits Glioblastoma Cells Proliferation Through Directly Targeting FOXP2 (Forkhead Box P2).
Zhang Hongbo H Li Yuntao Y Tan Yinqiu Y Liu Qi Q Jiang Shuting S Liu Dongyuan D Chen Qianxue Q Zhang Shizhong S
Frontiers in oncology 20191119
Glioblastoma (GBM) is the most malignant tumor in the central nervous system and the treatment is still unsatisfactory because the mechanism of the disease remains unclear. The abnormal expression of miRNAs and its target proteins play a crucial role in the development of glioblastoma. In this study, we demonstrated that high expression of miR-9-5p and low expression of forkhead box P2 (FOXP2) were related with better outcome in patients with GBM, and down regulated FOXP2 expression was able to ...[more]
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