Ontology highlight
ABSTRACT:
SUBMITTER: Ahn KC
PROVIDER: S-EPMC6882941 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Journal of Korean medical science 20191202 46
Accumulated evidence suggests that sporadic cases of Alzheimer's disease (AD) make up more than 95% of total AD patients, and diabetes has been implicated as a strong risk factor for the development of AD. Diabetes shares pathological features of AD, such as impaired insulin signaling, increased oxidative stress, increased amyloid-beta (Aβ) production, tauopathy and cerebrovascular complication. Due to shared pathologies between the two diseases, anti-diabetic drugs may be a suitable therapeutic ...[more]