Ontology highlight
ABSTRACT:
SUBMITTER: Thomas AS
PROVIDER: S-EPMC6884343 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Current Topics In Virology 20180101
It is widely accepted that an effective HIV-1 preventative vaccine must elicit antibodies that can block virus acquisition. Although, anti-HIV-1 broadly neutralizing antibodies (bnAbs) have been isolated, unfortunately, no vaccine immunogens have been designed that can elicit these bnAbs in uninfected at-risk individuals. Some studies have suggested that other antibody functionalities, besides neutralization, such as antibody-dependent cellular cytotoxicity (ADCC), may prevent HIV-1 acquisition. ...[more]