Ontology highlight
ABSTRACT:
SUBMITTER: Kinsella CM
PROVIDER: S-EPMC6884545 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Kinsella Cormac M CM Ruiz-Ruano Francisco J FJ Dion-Côté Anne-Marie AM Charles Alexander J AJ Gossmann Toni I TI Cabrero Josefa J Kappei Dennis D Hemmings Nicola N Simons Mirre J P MJP Camacho Juan Pedro M JPM Forstmeier Wolfgang W Suh Alexander A
Nature communications 20191129 1
In some eukaryotes, germline and somatic genomes differ dramatically in their composition. Here we characterise a major germline-soma dissimilarity caused by a germline-restricted chromosome (GRC) in songbirds. We show that the zebra finch GRC contains >115 genes paralogous to single-copy genes on 18 autosomes and the Z chromosome, and is enriched in genes involved in female gonad development. Many genes are likely functional, evidenced by expression in testes and ovaries at the RNA and protein ...[more]