Ontology highlight
ABSTRACT:
SUBMITTER: Hamze JG
PROVIDER: S-EPMC6884566 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Hamze Julieta Gabriela JG Canha-Gouveia Analuce A Algarra Blanca B Gómez-Torres María José MJ Olivares María Concepción MC Romar Raquel R Jiménez-Movilla María M
Scientific reports 20191129 1
The egg is a spherical cell encapsulated by the zona pellucida (ZP) which forms a filamentous matrix composed of several glycoproteins that mediate gamete recognition at fertilization. Studies on molecular mechanisms of sperm-egg binding are limited in many mammalian species by the scarcity of eggs, by ethical concerns in harvesting eggs, and by the high cost of producing genetically modified animals. To address these limitations, we have reproduced a three-dimensional (3D) model mimicking the o ...[more]